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The anal cancer foundation is currently supporting research studying vaccine-based immunotherapy treatments for patients with recurrent hpv-related cancers. The goals of this research are to identify targets on hpv-related cancers, including anal cancer, and to activate and train specific immune cells to selectively attack these targets on the cancer cells. For more general information on recurrence, you may also want to see understanding recurrence. Could i get a second cancer after treatment? People whove had anal cancer can still get other cancers. In fact, anal cancer survivors are at higher risk for getting some other types of cancer. Anal cancer recurrence is when cancer cells reappear after treatment, after a period of time during which no cancer was detectable. Recurrence can develop in the same area of the body, or can develop in other organs or tissues. A recent review of survival and recurrence in an unselected national norwegian cohort (n 328) over a 7-year observational period reinforced the finding that the current standard of concomitant chemoradiotherapy (based on the outcomes of 3 clinical trials) is very effective in anal cancer management 3, 4, 5, 6. These investigators reported curative outcomes in 87 of patients. Anal cancer treatment options include radiation therapy, chemotherapy, andor surgery. Get detailed information about newly diagnosed and recurrent anal cancer including risk factors, symptoms, diagnosis, prognosis, and treatment in this expert-reviewed summary. anal canal carcinoma (acc) is an uncommon disease accounting for only 3. 1 an estimated 3400 cases of acc will be diagnosed in the united states this year. 2 most of these tumors are cloacogenic, epidermoid, or squamous in origin. Treatment options depend on if the cancer comes back in or near the anus (called local recurrence) or if it recurs in another part of the body farther from the anus (called distant metastasis). The treatment options for a local recurrence of anal cancer depend on what was used to treat the original, or primary, tumour. Hi all - im a 47yo white male in nyc with recurrent anal cancer. I then underwent surgery and completed chemo radiation treatment in april 09. After a recent pet scan (23 sep) my oncologist advised of the recurrence and that the tumor is localised. Keywords anal cancer, anal canal, anal margin, chemoradiotherapy, hiv, hpv, salvage, recurrence, imaging introduction cancer of anal canal is uncommonly encountered and it makes upto 4 of all anorectal malignancies and 1.